Its not all about work!
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Development of transmission model for COVID-19 for each region in Illinois
During my master studies I spent 6 months in Tanzania to support data collection and analysis of the school survey, conducted by the National Malaria Control Programme.
Objectives of this project were to simulate varying larviciding deployment strategies and to determine coverage thresholds for targeting larvae vs adult mosquitoes.
During the MIM 2018, BioMalPar 2020, and ASTMH 2020 Manuela Runge reported from the conference as MESA correspondent (image from: mesamalaria.org/resource-hub/mim-2018-day-1) (
This project describes the use of mathematical modelling for planning of malaria intervention strategies embedded within the long-term collaboration between the Health Intervention Unit’s NETCELL project and the Infectious Disease Modelling Unit at the Swiss Tropical and Public Health Institute and the National Malaria Control Programme in Tanzania and other partners.
During my master studies I spent 6 months in Tanzania to support data collection and analysis of the school survey, conducted by the National Malaria Control Programme.
Published in Malaria Journal, 2018
Recommended citation: Chacky, F., Runge, M., Rumisha, S.F., Machafuko, P., Chaki, P., Massaga, J.J., Mohamed, A., Pothin, E., Molteni, F., Snow, R.W., Lengeler, C., Mandike, R., 2018. Nationwide school malaria parasitaemia survey in public primary schools, the United Republic of Tanzania. Malaria Journal 17, 452. https://doi.org/10.1186/s12936-018-2601-1
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Published in PLoS ONE, 2020
Recommended citation: Runge, M., Snow, R.W., Molteni, F., Thawer, S., Mohamed, A., Mandike, R., Giorgi, E., Macharia, P.M., Smith, T.A., Lengeler, C., Pothin, E., 2020. Simulating the council-specific impact of anti-malaria interventions: A tool to support malaria strategic planning in Tanzania. PLoS ONE 15, e0228469. https://doi.org/10.1371/journal.pone.0228469
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Published in Malaria Journal, 2020
Recommended citation: Runge, M., Molteni, F., Mandike, R., Snow, R.W., Lengeler, C., Mohamed, A., Pothin, E., 2020. Applied mathematical modelling to inform national malaria policies, strategies and operations in Tanzania. submitted to Malaria Journal.
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Published in Malaria Journal, 2020
Recommended citation: Thawer, S.G., Chacky, F., Runge, M., Reaves, E., Mandike, R., Lazaro, S., Mkude, S., Rumisha, S.F., Kumalija, C., Lengeler, C., Mohamed, A., Pothin, E., Snow, R.W., Molteni, F., 2020. Sub-national stratification of malaria risk in mainland Tanzania: a simplified assembly of survey and routine data. Malaria Journal 19, 177. https://doi.org/10.1186/s12936-020-03250-4
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Published in Infect Dis Model., 2020
Recommended citation: Armstrong, E., Runge, M., Gerardin, J., 2020. Identifying the measurements required to estimate rates of COVID-19 transmission, infection, and detection, using variational data assimilation. arXiv:2005.12441 [q-bio].
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Published in Malaria Journal, 2020
Recommended citation: Brunner, N.C., Chacky, F., Mandike, R., Mohamed, A., Runge, M., Thawer, S.G., Ross, A., Vounatsou, P., Lengeler, C., Molteni, F., Hetzel, M.W., 2019. The potential of pregnant women as a sentinel population for malaria surveillance. Malaria Journal 18, 370. https://doi.org/10.1186/s12936-019-2999-0
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Published in Malaria Journal, 2021
Recommended citation: Ozodiegwu, I.D., Ambrose, M., Battle, K.E., Bever, C., Diallo, O., Galatas, B., Runge, M., Gerardin, J., 2021. Beyond national indicators: adapting the Demographic and Health Surveys’ sampling strategies and questions to better inform subnational malaria intervention policy. Malaria Journal 20, 122. https://doi.org/10.1186/s12936-021-03646-w
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Published in BMC Public Health, 2021
Recommended citation: Holden, T.M., Richardson, R.A.K., Arevalo, P., Duffus, W.A., Runge, M., Whitney, E., Wise, L., Ezike, N.O., Patrick, S., Cobey, S., Gerardin, J., 2021. Geographic and demographic heterogeneity of SARS-CoV-2 diagnostic testing in Illinois, USA, March to December 2020. BMC Public Health 21, 1105. https://doi.org/10.1186/s12889-021-11177-x
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Published in Malaria Journal, 2021
A malaria transmission model, OpenMalaria, was used to simulate varying larviciding strategies and their impact on host-seeking mosquito densities, entomological inoculation rate (EIR) and malaria prevalence. Variations in coverage, duration, frequency, and timing of larviciding were simulated for three transmission intensities and four transmission seasonality profiles
Recommended citation: Runge, M., Mapua, S., Nambunga, I., Smith A.T., Chitnis N., Okumu F., Pothin E.. Evaluation of different deployment strategies for larviciding to control malaria: a simulation study. Malar J 20, 324 (2021). https://doi.org/10.1186/s12936-021-03854-4
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Published in Malaria Journal, 2022
Recommended citation: Runge, M., Thawer, S.G., Molteni, F., Chacky, F., Mkude, S., Mandike, R., Snow, R.W., Lengeler, C., Mohamed, A., Pothin, E., 2022. Sub-national tailoring of malaria interventions in Mainland Tanzania: simulation of the impact of strata-specific intervention combinations using modelling. Malar J 21, 92.
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Published in PLoS Global Public Health, 2022
Recommended citation: Runge M, Richardson RAK, Clay PA, Bell A, Holden TM, Singam M, et al. Modeling robust COVID-19 intensive care unit occupancy thresholds for imposing mitigation to prevent exceeding capacities. PLOS Global Public Health. 2022;2: e0000308. doi:10.1371/journal.pgph.0000308
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Published in medRXiv, 2022
Recommended citation: Toh KB, Runge M, Richardson RA, Hladish TJ, Gerardin J. Design of effective outpatient sentinel surveillance for COVID-19 decision-making: a modeling study. medRxiv; 2022. p. 2022.10.21.22281330. doi:10.1101/2022.10.21.22281330
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Published in Malaria Journal, 2023
Recommended citation: Runge, M., Stahlfeld, A., Ambrose, M. et al. Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modelling analysis. Malar J 22, 133 (2023).
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Published in Malaria Journal, 2023
Recommended citation: Ozodiegwu, I.D., Ambrose, M., Galatas, B. Runge M. et al. Application of mathematical modelling to inform national malaria intervention planning in Nigeria. Malar J 22, 137 (2023).
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Published in medRxiv (preprint), 2024
Recommended citation: Diallo OO, Diallo A, Toh KB, Diakité N, Dioubaté M, Runge M, et al. Subnational tailoring of malaria interventions to prioritize the malaria response in Guinea. medRxiv; 2024. p. 2024.06.26.24309532. doi:10.1101/2024.06.26.24309532
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Published in Vaccines, 2024
Recommended citation: Runge, M.; Karimian, Z.; Kheirandish, M.; Borghi, G.; Wodniak, N.; Fahmy, K.; Mantel, C.; Cherian, T.; Nabil Ahmed Said, Z.; Najafi, F.; et al. COVID-19 Vaccine Effectiveness Studies against Symptomatic and Severe Outcomes during the Omicron Period in Four Countries in the Eastern Mediterranean Region. Vaccines 2024, 12, 906.
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Coming soon! https://www.zotero.org/manuela.runge/collections/WEB7E7VT/items/GBULK39D/collection
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First attendance and talk at ASTMH! Click here for the recording (hosted at the MESA website).
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Modelling the impact of different larviciding deployment regimens to inform strategic planning
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Related publication here.
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View the report here